Crystal structure of the mitochondrial respiratory membrane protein Complex II

Design of wide spectrum inhibitors targeting the coronavirus main protease (M^pro)

Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus

Sun F, Huo X, Zhai YJ, Wang AJ, Xu JX, Su D, Bartlam M & Rao Z*. 2005. Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II. Cell, 121: 1043-1057. [download PDF]

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Yang H, Xie WQ, Xue XY, Yang KL, Ma J, Liang WX, Zhao Q, Zhou Z, Pei DQ, J. Ziebuhr, R. Hilgenfeld, K. Y. Yuen, Wong L., Gao GX, Chen SJ, Chen Z, Ma DW, Bartlam M & Rao Z*. 2005. Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. PLoS Biology, 3(10):e324, 1742-1752. [download PDF]

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He X, Zhou J, Bartlam M, Zhang R, Ma J, Lou Z, Li X, Li J, Joachimiak A., Zeng Z, Ge R, Rao Z* & Liu YF*. & 2008. Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature, 454(7208):1123-6. [download PDF]

ST news (www.stdaily.com) [download PDF]

Tsinghua University news [download PDF]

"Crowning achievement": Nature Research Highlights [download PDF]

"Common viruses have Achilles heel": New Scientist [download PDF]

"Casting a wide net to fight coronaviruses": PLoS Biology public release [download PDF]

"Casting a wide net to fight coronaviruses": PLoS Biology synopsis [download PDF]

"Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, Fodor E, Rao Z* & Liu Y*. 2009. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature, 458(7240):909-13 [download PDF]